Maternal Mastitis as a Risk Factor for Neonatal Parotitis
Primary author: Kyle Shelton, DO
Mentors: Natalie Royer, DO and Elizabeth Rodriguez‐Lien, MD
Acute neonatal parotitis is a rare disease, with approximately 75 cases reported between 1970 and
2022. The disease is characterized by swelling of the parotid gland, often unilateral, with associated
erythema and tenderness to the area. Fever, agitation, and dehydration are often associated with
parotitis. Prompt recognition of the condition allows for the initiation of antibiotic treatment and the
avoidance of complications. This case‐study describes a full‐term infant who presented with neonatal
parotitis. The history of present illness revealed that the patient’s mother had mastitis of one breast and
was actively breastfeeding. Mastitis of breastfeeding mothers has been implicated as a route for the
transmission of contaminated breastmilk to the infant and as a risk factor for the development of
neonatal parotitis.


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